While we do not manage a "mailing list" in the traditional sense, we do
send a lot of emails (daily/weekly/monthly reports, instant-alert
messages, etc.) where using VERP to track bounces could prove useful.
We run numerous projects with varying requirements and the messages
could be generated by Perl, Python, Bash/mutt, etc. All inbound/outbound
mail is routed through Postfix.
In my ideal world, I would find a magic setting that said, say, "use
VERP for all messages from ... at pinpointresearch dot com" or perhaps from
some specific IP range.